Advair inhaler contains fluticasone and salmeterol as active ingredients. These are used to treat COPD (chronic obstructive pulmonary disease) and asthma. Fluticasone is a corticosteroid similar to hydrocortisone secreted from the adrenal glands and Salmeterol belongs to a class of long acting bronchodilators.
The combination of these two drugs provides a better relief from asthma and is a very useful preventer medicine for chronic sufferers.
How Advair inhaler works
As stated above, Fluticasone is one of the most important corticosteroids used to treat asthma.
Corticosteroids alleviate the inflammation of the airways and in the lungs. Therefore, Fluticasone reduces swelling, prevents inflammatory reactions due to allergens, lowers irritations in the walls of the airways and small bronchioles, ultimately prevents narrowing of the air passages and so eases in the breathing.
Salmeterol is a long acting bronchodilator that relaxes the small air passages and airways in the lungs. It keeps airways dilated and makes a person breathe easier.
The combination of these two medicines makes the Advair inhaler a potent medication for asthma patients and especially useful in cases of chronic asthma.
Points to be remembered:
- Advair inhaler is not a rescue medicine for asthma. It is intended for treatment of chronic asthma and for long-term relief from symptoms.
- During acute episodes of asthma, you may need fast-acting reliever medicines such as Salbutamol and terbutaline.
- Treatment of asthma with Advair should not be given to children under the age of 4.
- Do not use Advair inhaler to manage sudden or severe attack of asthma or COPD. Always keep a reliever medicine with you for managing acute episodes of asthma.
- Chronic inflammation of airways
- For prevention of recurrent episodes of asthma
- COPD (chronic obstructive pulmonary disease)
- Long term management and prevention of asthma attacks in patients aged 4 years or older
Management of asthma in patients age 12 years or below:
One inhalation of 100/50 to 500/50 twice a day (Starting dose depends on the severity of asthma)
Management of asthma in patients age 4 to 11 years:
One inhalation of 100/50 twice a day
Maintenance therapy of COPD:
One inhalation of 250/50 twice a day
The dosage may vary for fluticasone propionate from 100 mcg to 500 mcg as explained above, but a dose of salmeterol will remain 50 mcg in all cases.
- Primary treatment of acute asthma
- Status asthmaticus
- Severe hypersensitivity to any of its ingredients, especially milk proteins
- Severe cases of COPD, which require intensive care or measures
Common Side effects of Advair inhalers:
- Throat irritation
- Infections – Upper respiratory tract
- Nausea and vomiting
- Oral Thrush
- Infections of ear, nose and throat in children are very common.
- People taking long acting beta2-adrenergic agonists including salmeterol, which is an active ingredient in Advair, are reported to increased risk of death from asthma.
- If breathing problems worsen while using Advair and you do not get relief from rescue medicine, get emergency medical care right away.
- Only use the Advair inhaler if your asthma is not well controlled with an inhaled corticosteroid alone.
- Risk of hospitalization for asthma is increased in case of children taking salmeterol.
If you experience any of the following symptoms or signs while using Advair, you should get emergency medical care immediately.
- Swelling of tongue, mouth or face
Worsen breathing problems